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Trazodone for sleep



  • Drug: Trazodone Hydrochloride
  • Strength: 50 mg
  • Pill Imprint: PLIVA 433
  • Color: White
  • Shape: Round
  • Drug: Trazodone Hydrochloride
  • Strength: 100 mg
  • Pill Imprint: PLIVA 434
  • Color: White
  • Shape: Round


Dosage form: oral tablet (100 mg; 150 mg; 300 mg; 50 mg)



Trazodone for sleep

Trazodone is an effective medication for sleep, as it helps people with insomnia achieve restful sleep. It has been used by people for decades, and is just as effective today as it was when it was first prescribed. The drug acts as a sedative, making it easier for the user to wind down and find the rest they need. Trazodone works by increasing serotonin levels in the brain, which helps to reduce stress and anxiety while also promoting a sense of calm.

It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression.

Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain.


You should not use trazodone if you are allergic to it, or if you are being treated with methylene blue injection.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, tranylcypromine and others.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using trazodone. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. Trazodone is not approved for use in children.

Before taking this medicine

You should not use trazodone if you are allergic to it.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

After you stop taking trazodone, you must wait at least 14 days before you start taking an MAOI.

How should I take trazodone?

This dug should be taken exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Take trazodone after a meal or a snack.

It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal when trazodone is taken with alcohol, barbiturates such as phenobarbital, or sedatives such as diazepam (Valium).

Trazodone for sleep side effects

Get emergency medical help if you have signs of an allergic reaction to trazodone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking trazodone and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a medical emergency and could lead to a serious condition that must be corrected with surgery.

Call your doctor at once if you have:

  • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
  • slow heartbeats;
  • unusual thoughts or behavior;
  • easy bruising, unusual bleeding; or
  • low levels of sodium in the body – headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.

Trazodone for dogs

Trazodone is a medication that is commonly used to treat depression in humans. It has also been found to be effective in treating anxiety and aggression in dogs. Trazodone works by increasing the levels of serotonin in the brain. This helps to improve mood and reduce anxiety.

Additional information


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